Hemp Protein: Number One Superfood

Effects of hemp seed protein powder alone and in combination with aerobic exercise on metabolic parameters, oxidative stress and neurotrophic factors in young sedentary men:

Summary
Hemp seed protein and physical activity (PA) have many benefits for the body's metabolic and brain health. This study investigated the effects of hemp seed protein alone and aerobic exercise on metabolic markers, oxidative stress, and neurotrophic factors in young sedentary men. This double-blind, placebo-controlled, randomized clinical trial was conducted on 48 sedentary young men in Tabriz, Iran, from April to August. In this study, the researcher randomized all participants into four groups: (1) hemp seed, (2) hemp seed + PA, (3) PA + placebo, and (4) placebo. Hemp seed supplements were administered as two 1 g capsules daily, and aerobic PA was performed three times per week. Anthropometric indices, dietary intake, antioxidant markers, lipid profile, fasting blood glucose (FBG), insulin, homeostatic model assessment for insulin resistance (HOMA-IR), quantitative insulin sensitivity control index (QUICKI), brain-derived neurotrophic factor (BDNF), neuropeptide Y (NPY), balance, reaction time and sit-up pull levels were assessed for all participants at baseline and post-intervention. We used ANOVA and ANCOVA analyses to compare oxidative stress and neurotrophic factors in all intervention groups. If the distribution of the response variable was not normal, the nonparametric equivalent of these tests was used (Wilcoxon and Kruskal-Wallis tests). All statistical analyses were performed using SPSS software version 23 and the significance level was accepted as 0.05 in all statistical tests. Aerobic PA combined with hemp seed consumption resulted in a significant difference in weight, body mass index, fat mass, high-density lipoprotein, catalase and BDNF compared to baseline. In addition, aerobic PA alone caused significant changes in body weight, fat mass, and triglycerides compared to baseline. Consumption of hemp seeds alone caused a significant increase in high-density lipoprotein levels compared to baseline. At the end of the study, fat mass, total cholesterol, low-density lipoproteins, and BDNF were significantly different between groups. According to our results, aerobic PA combined with hemp seeds consumption may improve anthropometric indices, lipid profile, and BDNF, and may improve health outcomes such as cardiovascular comorbidities, oxidative stress, and insulin resistance. PRACTICAL APPLICATIONS: A sedentary lifestyle has many health-threatening consequences such as cardiovascular comorbidities, oxidative stress, and insulin resistance. The importance of physical activity (PA) in improving these clinical signs is well known; however, the potential benefits of herbal therapy combined with FA in reducing the side effects of a sedentary lifestyle have not been well studied. In this study, we evaluated for the first time the benefits of hemp seed alone and in combination with aerobic exercise on metabolic markers, oxidative stress, and neurotrophic factors in young sedentary men. According to our results, aerobic PA combined with hemp seed consumption improved anthropometric indices, lipid profile, and brain-derived neurotrophic factor in young sedentary men.

Ali Mohammadrezaei 1, Ali Kavakeb 2, Mahdieh Abbasalizad-Farhangi 3, Mehran Mesgari-Abbasi 4
Connections expand
PMID: 36114824 DOI: 10.1111/jfbc.14417 It was translated into Turkish and published.

Original Link:

https://pubmed.ncbi.nlm.nih.gov/36114824/